LEHMANN; PAUL V (Total 20 Patents Found)

Embodiments of the present invention relate to devices and methods for detecting cellular products using detection particles having product-specific detection reagents and having a characteristic spectral feature. In particular, devices and methods are provided for measuring secreted cellular products including cytokin...
Embodiments of this invention include methods for detecting in vitro the presence in peripheral blood mononuclear cells (PBMCs), and in serum or plasma, of antibodies reactive to and of lymphocytes that are responsive to CNS antigens associated with Multiple Sclerosi (MS). These CNS antigens include, but are not limite...
The present invention relates to devices and methods for detecting cellular products, and in particular for measuring secreted cellular products, including cytokines. Microwells comprising hydrophobic membranes are described having greater capability to detect cytokines from individual cells in a mixture of heterogeneo...
Des modes de réalisation de la présente invention concernent des dispositifs et des procédés pour détecter des produits cellulaires au moyen de particules de détection qui présentent des réactifs spécifiques au produit et une composition spectrale caractéristique. Cette invention concerne notamment des dispos...
Embodiments of this invention include flatbed scanners that have a surface and have a plurality of light sources. Alternatively, a single light source can be moved in two dimensions relative to an object placed on the surface of the scanner. Other embodiments include a scan head that is moveable in two dimensions relat...
Dans de nombreux modes de réalisation de l'invention, des scanners à plat comprennent une surface et une pluralité de sources lumineuses. En variante, une seule source lumineuse peut être déplacée dans deux dimensions par rapport à un objet placé à la surface du scanner. Dans d'autres modes de réalisa...
Embodiments of the present invention relate to devices and methods for detecting cellular products using detection particles having product-specific detection reagents and having a characteristic spectral feature. In particular, devices and methods are provided for measuring secreted cellular products including cytokin...
Des modes de réalisation de cette invention comprennent des procédés de détection in vitro de la présence dans des cellules mononucléaires du sang périphérique (PBMC) et dans le sérum ou le plasma, d'anticorps et de lymphocytes réactifs aux antigènes SNC associés à la sclérose en plaques (MS). Ces a...
Des modes de réalisation de la présente invention concernent des dispositifs et des procédés pour détecter des produits cellulaires au moyen de particules de détection qui présentent des réactifs spécifiques au produit et une composition spectrale caractéristique. Cette invention concerne notamment des dispos...
Embodiments of the present invention relate to devices and methods for detecting cellular products using detection particles having product-specific detection reagents and having a characteristic spectral feature. In particular, devices and methods are provided for measuring secreted cellular products including cytokin...
Embodiments of this invention include flatbed scanners that have a surface and have a plurality of light sources. Alternatively, a single light source can be moved in two dimensions relative to an object placed on the surface of the scanner. Other embodiments include a scan head that is moveable in two dimensions relat...
Embodiments of the present invention relate to devices and methods for detecting cellular products using detection particles having product-specific detection reagents and having a characteristic spectral feature. In particular, devices and methods are provided for measuring secreted cellular products including cytokin...