val (Total 370 Patents Found)

Val (370 Patents Found)
Combinations of cyclo-(N-methyl-Ala-Tyr-D-Trp-Lys-Val-Phe) and a NSAID have been found to exhibit much lower gastric lesions or ulcers than normally associated with NSAIDs and are thereby clinically useful in long-term therapy for patients suffering from chronic rheumatoid arthritis or osteoarthritis....
The invention relates to a cyclic peptide which is provided with a residue fragment of -Val-Sta-Leu- and is used as immunosuppressive agents, and the synthesis process of the cyclic peptide (Ile-Ile-Pro-Pro-Tyr-Val-Sta-Leu) consists of 1) removing amino-protecting groups, 2) transpeptidase reaction, 3) the cutting of a...
A pharmaceutical composition and granulates, prepared by a wet granulation process. The pharmaceutical composition and granulates contain a therapeutic compound, e.g., the 3'-L-valine ester of .beta.-D-2'-C-methyl-riboguranosyl cytidine valopicitabine (val-mcyd) and its salts, esters, prodrugs or derivatives....
A process for preparing an emulsion composition comprising a cyclosporin, a rapamycin or an ascomycin or a derivative thereof as active agent, which process comprises the step of admixing to a placebo fat emulsion a concentrate comprising a) the active agent, b) a stabiliser selected from a phospholipid, a glycolipid, ...
The invention relates to a process for the specific isotopic labeling of Valine, Leucine and Isoleucine amino acids. The process of the invention uses a 2-alkyl-2-hydroxy-3- oxobutanoic acid in which the alkyl substituent in position 2 is ethyl or methyl. The invention can be used for the analysis of proteins, in parti...
A preparation comprises a herbal extract and/or fraction, and a pharmaceutical preparation includes extract of Curcuma mangga Val. et Zipp., which has bioactivities in reducing expression levels of 5-alpha-reductase-1, androgen receptor, and PI3 in prostate cancer cells. The use of this present invention is directed ...
The invention discloses a conjugate of a peptide chain and two fatty alcohol chains, a preparation method thereof and medicinal application thereof. The conjugate is formed by conjugating one Arg-Gly-Asp-Val chain and two fatty alcohol chains by Asp and has a general formula of Arg-Gly-Asp-Val-Asp[OCH2(CH2)nCH3]2, wher...
La présente invention concerne l'utilisation du composé peptidique Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu-OH en tant qu'agent thérapeutique pour la prophylaxie et/ou le traitement du cancer, de maladies auto-immunes, de maladies fibreuses, de maladies inflammatoires, de maladies neur...
THE PRESENT INVENTION PROVIDES THE PENTACOSAPERPTIDES OF GENERAL FORMULA D-SERYL-L-TYROSYL-L-SERYL-L-NORLENCYLX-L-HISTIDYL-L-PHENYLALANYL-L-ARGINYL-L-TRYPTOPHANYL-GLYCYL-L-LYSYL-L-PROTYL-L-VALYL-GLYCYLL-LYSYL-L-LLYSYL-L-LYSYL-L-LYSYL-L-PROLYL-LVALYL-L-LYSYL-L-VALYL-L-TYROSYL-L-PROLYL-L-VALINAMIDE, IN WHICH X SIGNIFIES ...
Two or more run-val mapping tables are selected to encode different subsets of video signals of a sequence of video signals. Each run-val mapping table is selected to map a particular set of run-val pairs to a corresponding set of run-val codes. Each run-val pair comprises a run and a val, the run corresponding to a le...
The invention relates to a process for the specific isotopic labeling of Valine, Leucine and Isoleucine amino acids. The process of the invention uses a 2-alkyl-2-hydroxy-3-oxobutanoic acid in which the alkyl substituent in position 2 is ethyl or methyl. The invention can be used for the analysis of proteins, in partic...
本发明属于生物技术领域,具体涉及一种聚酯连接的三价铁次血红素六肽及其制备方法。其首先在无水无氧条件下制备聚酯-NHS酯,然后与次血红素混合以DMSO为溶剂反应;反应结束后在水中将聚合物沉出,离心,收集沉出物,纯化干燥后,即得...
Subtilisin protease (I) that has, at positions homologous to positions 230, 256 and 259 of subtilisin BPN' from Bacillus amyloliquefaciens, the amino acids (aa) Val, Gly and Asn, respectively, is new. Independent claims are also included for the following: (a) subtilisin proteases (II) that have: (i) at homologo...
The present invention is directed to the use of the peptide compound Thr-Thr-Ser-Gln-Val-Arg-Pro-Arg-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular...